methylation

美 [meθɪ'leɪʃ(ə)n]英 [meθɪ'leɪʃ(ə)n]
  • n.甲基化作用
  • 网络甲基化酌;甲基化反应;甲基化药物

methylationmethylation

methylation

甲基化

甲基化 (methylation) 进行之前,dUDP会先移除一个磷酸根,转变成dUMP。然后胸苷酸合成酶 (thymidylate synthetase) 加 …

甲基化作用

怎么吃,也毒不了我 ... 2氨基酸结合作用( AminoAcidConjugation) 3甲基化作用( Methylation) 4硫酸化作用( Sulfation) ...

甲基化酌

化工英语常用词汇J - 译帮专业英语在线翻译 ... 甲基化物 methide 甲基化酌 methylation 甲基环己醇 methylcyclohexanol ...

甲基化反应

  甲基化反应(methylation)有机化合物分子中的氢被甲基(-CH3)取代的反应。苯与卤甲烷在三氯化铝等催化剂作用下可发生甲基化 …

甲基化药物

...、促进细胞凋亡的新药、蛋白质/多肽类“生长因子”、甲基化药物Methylation)、P-53肿瘤抑制素蛋白质、RAS蛋白质、调 …

甲基化结合

四、甲基化结合methylation) 74 五、氨基酸结合(conjugation with amino acids) 74 六、谷胱甘肽或巯基尿酸结合(glutat…

甲基根

...促进区 (promoter region)常被接上甲基根(methylation),其中组织蛋白(histone)的甲基化显得相当重要,因为会影响染色体的 …

1
Methylation, the addition to a base of a group of three hydrogens and a carbon atom, is one way in which genes are regulated. 甲基化就是在一个碱基上加上一个由三个氢原子和一个碳原子组成的基团。它是一种基因调整的方式。
2
Researchers looked for - and found - a chemical change called DNA methylation in healthy tissue adjacent to breast tumors. 研究者寻找并发现了靠近肿瘤组织的健康组织中有“DNA甲基化”这种化学改变。
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Scientists have several reasons to suspect that this methylation pattern might contribute to autoimmunity . 有数个理由使科学家怀疑,甲基化的模式可能会影响自体免疫。
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Consistent with these important roles, a growing number of human diseases have been found to be associated with aberrant DNA methylation. 越来越多的人类疾病被发现同DNA甲基化的异常有关。
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In malignant cell the pattern of DNA methylation, as well as the set of DNA methyltransferase activities, differs from that in normal cell. 在恶性肿瘤细胞中,DNA甲基化模式,以及一套DNA甲基转移酶活性不同于正常细胞。
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DNA methylation is one of the most common epigenetic events occurring in human genome and is implicated in cancer. DNA甲基化是人类基因组发生最为常见的一种表观遗传学事件,因而研究甲基化与肿瘤的关系成为当前分子生物学的热点之一。
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METHODS Sugar composition analysis, methylation analysis and NMR were used to determine the structural features. 方法采用糖组成分析、甲基化分析以及NMR确定该多糖的结构。
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This results in a considerable reduction in the time required for completion of a detailed genomic methylation project. 这种结果相当大的减少了完成一个详细的基因组甲基化项目所需要的时间。
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Methylation is an epigenetic modification to one's DNA that changes a gene's activity, generally reducing that activity within the genome. 甲基化作用是对DNA的后天修改,并改变基因活动,通常是在基因组内减少这个活动。
10
It can be thus suggested, that the plant cell contains at least two different, and probably, interdependent systems of DNA methylation. 因此能够建议,植物细胞包含至少两种不同,可能相互依赖的DNA甲基化系统。
11
In the case of stress, previous studies have suggested that methylation of the gene which encodes glucocorticoid receptors is important. 在“抑郁母亲”的案例中,先前的研究提出,以糖皮质激素受体编码的基因的甲基化起到了很重要的最用。
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Methylation of cytosine residues is one of the most versatile mechanisms of epigenetic regulation. 胞嘧啶残基的甲基化是表观遗传调控的最复杂的机制之一。
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Bisulphite genomic sequencing is a widely used technique for detailed analysis of the methylation status of a region of DNA. 亚硫酸氢盐基因组测序是详细分析一个区域的DNA甲基化状态的一种广泛使用的技术。
14
The aetiology of RSS is still unclear but it has been correlated with the degrees of gene methylation. 目前,导致RSS的病因仍不明瞭,但近来研究显示可能与部分基因的甲基化程度有关。
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Whether cytosine methylation is the explanation for this difference has yet to be tested, but something is clearly happening. 胞嘧啶甲基化是否能够解释这种差异还有待考察,但是的确是有些什么东西存在着。
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DNA methylation is a chemical modification made to DNA that plays an important role in dictating how DNA is read and interpreted by a cell. DNA甲基化是一个化学修饰,它在让细胞正确的解读DNA的过程中起着重要的作用。
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The work is one of several clues that DNA methylation affects the formation and maintenance of memories. 这项工作是DNA甲基化影响记忆形成和延续的线索之一。
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One of the best known epigenetic factors is DNA methylation, which is a major mechanism for regulation of gene expression. 表观因子中最著名的一个是DNA甲基化,它是基因表达调控的一个主要机制。
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Therefore, profiling DNA methylation across the genome is vital to understanding the influence of epigenetics. 因此,跨基因组的DNA甲基化谱对于理解表观遗传学的影响是极其重要的。
20
For how the methylation was involved in muscle development and myogenin gene regulation precisely requires further study to prove. 至于甲基化是如何参与肌肉的发育和肌细胞生成素基因的精确调控的尚需进一步研究证明。
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DNA methylation is an important epigenetic modification which regulates a number of biological processes. DNA甲基化作为一种重要的表观遗传修饰,调节着机体许多生物学过程。
22
Malignant gliomas often have the MGMT gene inactivated due to aberrant methylation of its promoter region. 恶性神经胶质瘤经常有MGMT基因被撤消的由于它的促进者区域的出轨甲基化。
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Genes suppressed by this methylation include tumor suppressors that would otherwise prevent cancer growth and spread. 被该甲基化抑制的基因包括通过其它方式预防肿瘤生长与扩散的肿瘤抑制基因。
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Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials. 靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
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DNA methylation is one of the most common epigenetic events in eukaryotic cell. DNA甲基化是真核细胞基因组最常见的一种表观遗传学修饰。
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However, then injecting them with a drug to inhibit methylation seemed to erase any memory of the shock. 然而,在给它们注射了抑制甲基化作用的药物后,它们对于电击的记忆似乎就完全被消去了。
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The inactivation of antioncogene by methylation has become one of important pathogenesis mechanisms of leukemia. 抑癌基因甲基化失活已成为白血病发生的重要机制之一。
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Results indicate that the primary productivity is an important indicator of Hg methylation in reservoirs. 以上研究表明,初级生产力水平是水库汞甲基化的重要影响因素。
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The code written on his tones consists of post-translational modifications, including acetylation and methylation. 代码写在蛋白包括翻译后的修改,包括乙酰化和甲基化。
30
What happens to the unbranched glucose residues in amylopectin during the methylation and hydrolysis procedure? 在甲基化和水解过程中不分支的葡萄糖残基会发生什么变化?