microrna
- 网络微型核糖核酸;微核糖核酸;微小核糖核酸
microrna
microrna
微型核糖核酸
微型核糖核酸(microRNA)研究与疾病协会:2010年市场报告MicroRNA Research and Disease Associations 2010 Market Re…
微核糖核酸
...)报道,美国科学家不借助干细胞移植过程,而使用名为微核糖核酸(microRNA)的分子,在实验室器皿中首次将实验鼠心 …
微小核糖核酸
微小核糖核酸(microRNA)是一类长约19至24个核苷酸的非编码小分子RNA,它通过与靶基因的信使RNA(mRNA)结合的 …
微核醣核酸
微核醣核酸(microRNA)在生长、细胞分化和疾病都扮演相当重要的角色。然而之前许多相关研究大都观察单一个微核醣核酸的 …
微小核醣核酸
微小核醣核酸 (MicroRNA)属於一种短片段、未转译之核醣核酸。微小核醣核酸被指出参与细胞内诸多调节机制,也可能调控讯 …
核酸分子
小核酸分子(microRNA)是21世纪生命科学的最伟大发现之一,在发育、凋亡、代谢以及人类疾病方面起着重要的调控作用。…
微型核醣核酸
微型核醣核酸(microRNA)在植物体内所扮演的调控性角色林淑怡、邱子珍 农生中心 1091 86 是「旧瓶装新酒」?
1
Although microRNAs do not code for proteins, they prevent specific genes from giving rise to the proteins they encode.
尽管MicroRNA并不是指导蛋白质合成的密码,但是他们会阻止一些特定基因的表达(合成相应蛋白质)。
2
A number of miRNA genes were shown to be located in fragile regions of the human genome that are associated with cancer 8.
研究结果证实,许多microRNA基因存在于那些与癌症有关的人类基因组脆弱区域。
3
The microRNA, miR164, has been implicated in aging in Arabidopsis and was part of a complex genetic chain that changed as leaves aged.
其中MIR164这个微RNA,在Arabidopsis的衰老进程中被确认是一个复杂遗传链条的部分,那链条随着树叶的衰老而变化。
4
The next step is to find ways to modify this microRNA in the setting of disease and test its ability to alter the disease process.
接下来要做的是怎样在疾病环境中调控干扰RNA并检测它改变疾病过程的能力。
5
However, if a miRNA biomarker fingerprint can be established, a more accurate assessment would be more likely.
然而,如果一个microRNA指纹库得以建立,更准确的评估将变得可能。
6
The mature miRNA is incorporated into an RNA-induced silencing complex that binds to a target messenger RNA (mRNA).
成熟microRNA与目标mRNA结合,形成了RNA诱导的基因沉默复合体。
7
A sera-miRNA fingerprint was determined for colorectal cancer as well.
血清microRNA指纹同样能很好地诊断结肠癌。
8
brains of Parkinson's patients to determine which type of microRNA was noticeably deficient in the midbrain regions.
下一步,这些研究人员检测了帕金森病人死后的脑部以确定哪种信使RNA在中脑区域是明显缺乏的。
9
Besides human leukemias and lymphomas, microRNA genes also have been found in human lung, breast and colon cancers .
除了人类的白血病和淋巴癌,人类肺癌,乳腺癌和结肠癌中也发现了微RNA基因。
10
No study has evaluated the association between microRNA expression patterns and colon cancer prognosis or therapeutic outcomes.
但是现在尚无有关研究来评估microRNA的表达形式与结肠癌预后或治疗结果的相关性。
11
A potential site of action for the microRNAs aligns to an area in a human gene, NR4A3, that encodes a transcription factor protein.
在人类的基因组中有一个部位用于解码蛋白质转录因子,我们称之NR4A3,是microRNA的潜在作用部分。
12
Through various techniques, numerous groups have gone on to show that different cancer types have distinct miRNA profiles.
应用各种不同的技术,许多研究小组一直在试图寻找不同癌症的特异性microRNA表达谱。
13
Meanwhile, these studies show that analyzing miRNA levels in serum is a promising area for identifying biomarkers of cancer.
同时,这些研究也证实,血清microRNA的测定是一个检测癌症生物学标志物很有前途的领域。
14
The study examined human pancreatic tumor tissue and compared it to nearby normal tissue and control tissue for levels of microRNA (miRNA).
该研究检测比较了人类胰腺癌组织与周围的正常组织和对照组织中小分子RNA(miRNA)水平。
15
Although first discovered in C. elegans, miRNAs have since been shown to be involved in human cancers 5.
虽然最早在线虫体内发现,但已经证明,microRNA能参与人类癌症的发生。
16
Therefore, it remains elusive if and when there will be room for new, microRNA-based biomarkers.
因此,是否以及何时将有空间给予新的、基于微RNA的生物标记物仍然是难以捉摸的。
17
The good news is Croce says the technology to manipulate the activity of microRNA already exists.
好消息是,c说抑制微RNA活动性的技术已经存在了。
18
A more recent paper has also emphasized the role of micro-RNA in hepato-carcinogenesis.
最近有一篇文章则强调了microRNA在肝癌形成中的作用。
19
This microRNA cluster could represent a new therapeutic target for treating tumors caused by Rb deficiency.
这种miRNA簇可以为治疗Rb缺失引致的肿瘤提供新的靶点。
20
The group also found that in young leaves ORE1 was held in check by microRNA, a kind of small molecule that controls gene expression.
该团队还发现在年轻树叶里Ore1含量由微RNA(一种控制基因表达的小分子)控制。
21
Small pieces of RNA called microRNAs help control gene activity and orchestrate development in plants and animals (ScienceNOW, 8 July 2002).
一种称为“microRNA”的小片段RNA有助于控制动植物体内的基因活性及其发育。
22
Furthermore, miRNAs are continuously being shown to act as both oncogenes and tumor suppressors 5.
此外,microRNA基因还不断被证实扮演着原癌基因和抑癌基因的角色。
23
Blood samples from 21 volunteers were tested for the presence of microRNAs from crop plants, such as rice, wheat, potatoes and cabbage.
21位志愿者的血液样本被用来检测来自各种农作物(比如大米,土豆,和卷心菜)的MicroRNA的存在。
24
The first serum-miRNA biomarker discovered was miR-21. Lawrie et al.
第一个被发现的血清microRNA标志物是miR-21。
25
So Crochi's team purposely altered a single type of microRNA gene in lab mice.
所以克里奇的小组在实验室小鼠身上有目的地改变一个小RNA基因。
26
Many miRNAs are well conserved across species, suggesting an important role for them.
许多microRNA在不同物种间非常保守,暗示了它们的重要地位。
27
In the sera of lung cancer patients, there were 63 miRNAs that were not found in normal sera.
在肺癌患者的血清中有63种microRNA是健康人血清中所不存在的。
28
miRBase (Release 12. 0), the central database for miRNAs, lists over 8 000 miRNAs from plants, animals and viruses.
microRNA的中心文库——miRBase(Release12.0)包含了超过8000种植物、动物和病毒的microRNA。
29
A streamlined representation of the interplay between transcriptionfactors in the roundworm. Image: Science
蛔虫转录因子和microRNA之间相互作用的精简表示。
30
Effects of MicroRNA 122 on Gene Expression Profiles of Hepatocellular Carcinoma Cells
122对肝癌细胞基因表达谱的影响