PRION
美 [ˈpriɑn]英 [ˈpraɪɒn]
- n.朊病毒（能导致脑病）
- 网络朊毒体；朊粒；朊蛋白
复数：prions
PRIONPRION
朊病毒
朊病毒病即海绵状脑病是由朊病毒（Prion）引起的人和动物中枢神经系统病变性致死疾病。
朊毒体
...菌消毒流程，即就算把牛肉煮熟，依然无法消灭朊毒体朊毒体 （prion），中文译名有「蛋白质感染因子」、「蛋白侵染子」 …
朊粒
朊粒（prion）是一种生物学地位尚未确定的蛋白质传染因子，不含核酸，人主要因食入感染朊粒的动物肉类而感染，主要引起 …
朊蛋白
4．什么是朊蛋白(Prion)，以及它的发现有什么意义？1．请详述乳糖操纵子正负调控机制，并结合此机制解释基因重组技术中 …
普恩蛋白
普恩蛋白(PRION)很硬命,耐热性很高,所以有时煮熟了它还是有致病力,它有特殊的化学结构,特别的是它像魔法师一样能够将正 …
阮病毒
阮病毒（prion）可以引起同种或异种蛋白质构象改变而致病或功能改变的蛋白质，是引起传染性海绵样脑病(疯牛病)的蛋白质。 …
感染性蛋白质
感染性蛋白质（Prion），一种形体变异的蛋白质分子，通常被人们认为能引起疾病或具有传染性。与病毒、细菌等传染性介质 …
1
Therefore, many investigators are looking at ways to block prion formation or to boost a cell's ability to clear existing prisons.
因此，许多研究人员正在想办法阻断普恩蛋白的形成，或是提升细胞清除既存普恩蛋白的能力。
2
But if an absence of healthy prion protein was severely detrimental, then we might have to rethink this therapeutic approach.
但是如果能证明CJD确实是由小蛋白的缺失造成的，那么我们就会重新考虑治疗方法。
3
And the mouse prisons were able to change the hamster proteins into a new kind of prion that infected both healthy hamsters and mice.
老鼠朊蛋白能把仓鼠蛋白变为一种新的朊蛋白，这种新的朊蛋白能感染健康的仓鼠和老鼠。
4
The cause of FSE is an infectious agent called a prion, and prion protein accumulates in the brain tissue as a substance called amyloid.
FSE的病原是一种感染性蛋白，这种感染性蛋白像淀粉质一样在脑组织积累。
5
Although PrP(C) is encoded by the host genome, prions themselves encipher many phenotypic TSE variants, known as prion strains.
虽然蛋白（c）是编码的宿主基因组，朊病毒本身加密型谢志伟许多变种，称为朊病毒株。
6
However, prion diseases are considered to be representative of other protein precipitation-associated diseases .
然而，阮病毒疾病被认为是其他蛋白相关疾病的典型。
7
The origin of the crisis was the feeding of cattle with animal feed that was contaminated by a new pathogenic agent - a prion.
这场危机起源于使用动物饲料喂养牛，这些动物饲料都被一种新的致病体—朊蛋白污染了。
8
There's hope that by disentangling PrP's normal job, prion diseases will become easier to understand.
PrP及朊病毒疾病的的常规研究将有可能变得更加容易理解。
9
Not all organisms are killed by sterilizing processes in pet food, and you do not understand the role prion proteins play.
并非所有的有机体都可以在宠物食品的消毒过程中被消灭，你还不理解朊病毒蛋白质所扮演的角色。
10
Prion diseases are always fatal, often, however, not until months after the outbreak of the disease. As yet there is no cure.
朊病毒病是致命的，常常在发病后数月死亡，但是目前还没有有效的治疗方法。
11
In 2003, Mead and his colleagues discovered a much more common variant of the prion gene that provides protection against prion diseases.
2003年，米德和他的同事发现了朊病毒基因更普遍的变体，可以抗御与朊病毒有关的疾病。
12
Prion diseases affect the brains of a number of mammals, including humans.
朊病毒疾病能影响许多哺乳动物的大脑（包括人类）。
13
However, the prion protein in scrapie-infected brain tissue differs from normal prion protein in some of its properties.
然而，在感染羊瘙痒病的大脑组织的普利昂蛋白在某些性质上不同于一般的普利昂蛋白。
14
The prion-like folding behavior of a multimer, consisted of 27 individual model proteins, is studied with simple lattice model.
我们利用简单的格点模型来研究由27个单体蛋白聚集成的多聚体的类疯牛病蛋白折叠行为。
15
The malformed prion proteins can be deposited in the brain, thereby destroying brain tissue.
致病性的朊病毒蛋白质在脑中沉积并损伤脑组织。
16
We have shown an initial proof of this principle by following the evolution of prion disease in mice.
我们藉由追踪实验小鼠体内普恩蛋白疾病的进展，对这个理论有了初步的验证。
17
When these MRI findings are observed in an appropriate clinical context, the diagnosis of prion disease is very likely.
当这些MRI表现是在一个适当的观察临床方面，朊病毒疾病的诊断是非常可能的。
18
CJD is a progressive fatal neurodegenerative disorder caused by prion proteins accumulating within the neurons.
CJD是一种进行性致命性神经变性疾病，是由于朊病毒在神经元内堆积所致。
19
When he added an anti-prion drug to the mix, though, the virus production halted.
而混合了抗朊病毒药物后，老病毒的生产就停止了。
20
Surgeon or Designee will notify the Operating Room of the brain biopsy of suspected prion disease.
外科医生或操作者应通知可疑朊毒体病人进行脑组织活检的手术室。
21
Several manufacturers have also addressed the concern over prion transmission.
一些制造商们还讨论了关注朊病毒传染。
22
Until that question is answered, the new era of the prion will remain confusing and frightening.
如果这一问题得不到解答，朊病毒的新时期将仍然充满困惑和恐惧。
23
Although the wastewater generated from the experiment was clear of prion protein presence, the biosolids were not.
虽然实验产生的废水中没有朊病毒出现，但废水处理产生的污泥却并非如此。
24
Still, scientists say new forms of prion diseases have arisen lately, and there's concern that they could hop to humans.
尽管如此，科学家说近来出现了一些新的朊病毒疾病，人们担心这些疾病可能会传播到人类身上。
25
Prion diseases can be controlled, if not eradicated.
如果说普朊病难以彻底消除的话，那也是可以控制的。
26
More importantly, preliminary results suggest they are effective at extending the lives of prion-infected mice.
更重要的是，初步的实验结果提示这些分子能有效延长朊病毒感染小鼠的寿命，
27
They discovered that amyloid beta binds to the prion proteins normally found on neurons.
研究人员发现与，淀粉样蛋白与通常是在神经元上发现的朊病毒蛋白结合在一起。
28
Together with his colleagues, he studied four different strains of mice lacking the gene for the prion PrPC.
他和他的同事们研究了四种缺少这种蛋白基因的老鼠。
29
There is currently no treatment for prion diseases, which include CJD in humans and bovine spongiform encephalopathy (BSE) in cattle.
目前还没有普粒子疾病的治疗办法，包括人类的克雅氏病（CJD）和牛脑海绵状病（疯牛病，BSE）。
30
The canine family is evidently immune to prion diseases, but felines can contract them.
目前已证实犬科动物对普恩蛋白疾病免疫，但猫科动物有可能感染。